top of page

Magnesium Depleted by Numerous Drugs

Dr. Linda J. Dobberstein, DC, Board Certified in Clinical Nutrition


Magnesium is a critical nutrient that impacts numerous systems through the body. Low quality diets, changes to nutrient content in the soil and foods, and high stress all reduce tissue stores of magnesium and produce a deficit situation that is unable to meet demand. This deficit takes a toll on health and can lead to long-term health issues. On top of these dietary and lifestyle challenges, there is the added issue in that several commonly used drugs significantly deplete nutrients including magnesium. With the added demands for magnesium in our life, we must be mindful on what helps or hinders this life essential mineral.


Why You Need Magnesium


Lack of adequate magnesium may cause fatigue, sleep problems, muscle cramps including foot and leg cramps, mood stress, irritability, weakness, and poor appetite.


Hundreds of processes in all your organs require magnesium. Here is a snapshot of some of these processes that depend upon adequate magnesium. Your heart and cardiovascular system require magnesium for its rhythm, quality of heartbeat, and blood vessel relaxation. Blood sugar metabolism, liver detoxification, immune cell functions and protection, gastrointestinal function and bowel movements require adequate magnesium.


Bones, joints and cartilage require magnesium for structure, but also to help other nutrients like calcium and vitamin D work synergistically together. Magnesium status even affects dental implants and restoration therapy because of bone health and tissue inflammation management.


Your energy producing mitochondria absolutely need magnesium. If mitochondria are not provided enough nutrients like magnesium, the very essence of energy production within each organ is compromised. This is particularly critical for your brain, immune system, thyroid and adrenal stress tolerance and exercise tolerance.


Prenatal development and pregnancy require adequate magnesium. Bone health in menopause is significantly influenced by magnesium status. Men need magnesium for prostate health and urine flow.


Even the repair mechanisms for your DNA require magnesium. If you do not have enough magnesium, your DNA is more susceptible to oxidative stress and injury.


About 400 mg per day of magnesium is needed for adults to meet the RDA. Any of the factors listed above will increase your daily need. Further information about magnesium including food sources and lab test information are in the articles below.


Insufficient Magnesium – Public Health Crisis Declared


Magnesium: A Notable Mineral Essential for Life


Vitamin D and Magnesium: Essential Partnership for Health


How to Choose a High Quality Magnesium Supplement


Magnesium Boosts Brain Function