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Performa Plus: Newly Enhanced for Circulation, Endurance, and Exercise

Dr. Linda J. Dobberstein, DC, Board Certified in Clinical Nutrition


We are excited to announce the return of Performa Plus. This newly enhanced formula supports the body’s natural production of nitric oxide. This is important for blood pressure regulation and vasodilation, circulation and blood flow, muscle stamina, exercise capacity, and male performance. It also supports mental focus, enhances metabolism and fat burning, and has a host of other benefits. Increasing healthy nitric oxide is a powerful way to improve overall exercise and physical performance. This enhanced formula now contains Nitrosigine®, a patented form of arginine. This improvement aids in absorption and usability and provides noticeable results. It still includes grape seed extract and Panax ginseng for a great synergistic blend of nutrients for your various performance needs. L-Arginine and Nitrosigine® L-Arginine is an important amino acid that is needed to produce nitric oxide and improve blood flow and vasodilation. It is also used in other activities like wound healing, immune system activity and recovery, and removal of ammonia from your tissue. During stress, illness, or injury, your body needs more conditionally essential amino acids like arginine and others such as glutamine and taurine. Although arginine is important for many key processes, there are challenges when trying to boost tissue levels through supplementation. Basic L-arginine has poor absorption in the digestive tract and even less activity in the blood stream. The nutrient form called Nitrosigine®, or inositol-stabilized arginine silicate, has much better absorption and activity and works faster than plain L-arginine. It can get into your blood stream in as fast as 15 minutes and stays in your system up to 6 hours for long-lasting effects and performance. This makes a substantial impact in the amount of usable arginine in your blood stream. Basic arginine absorption pales in comparison. Inositol, a B-vitamin like compound and natural sugar along with silicate, a natural trace mineral found in fruits, vegetables, water, and the earth help supercharge arginine’s absorption and utilization in your body. Athletic Performance Nitrosigine® is highly desired by those who participate in sports, due to its effect on performance improvements. It enhances blood flow to muscles, cardiovascular system, and brain. This aids muscles and recovery, focus, mental acuity and energy, and boosts sports performance. The improvements, while critical for athletes, benefit others in their daily life. Nitrosigine® Studies Human clinical trials published in the February 2020 edition of the Journal of the International Society of Sports Nutrition demonstrated the effectiveness of Nitrosigine®. This randomized control trial evaluated the effects of Nitrosigine® on healthy adult athletes. Participants were given placebo, 1500 mg of Nitrosigine®, or 8000 mg of citrulline malate in three different trials. Citrulline is a precursor to arginine but takes markedly more product to produce the same effect. Blood vessel dilation effects were measured before and 60 minutes after ingestion using ultrasound and flow mediated dilation. Nitrosigine® and citrulline significantly enhanced flow mediated dilation more than 30 percent. Study results showed that improved blood flow to skeletal muscles can result in “potential improvements in exercise performance.” Benefits More Than Sports Performance This advanced form of arginine aids more than physical sports performance. Several studies show that Nitrosigine® is helpful in cognitive tasks and benefits tissue repair. A randomized controlled trial published in the journal Nutrients November 2021 evaluated cognitive outcomes in healthy young adults. Participants completed thorough neuropsychological testing that evaluated immediate memory, visual-spatial and visual-recognition, language, attention, processing speed, decision making, and delayed memory prior to and after receiving 1500 mg of the enhanced arginine or placebo. Results showed that those who received Nitrosigine® experienced “significantly improved” overall cognitive function, and immediate and delayed memory recall. Enhanced arginine also supports other perimeters related with tissue healing. Several animal studies reveal Nitrosigine’s® effect with accelerated healing in skin wounds, joint health, periodontal health, and bone health. Improvements were identified with modulation of several inflammatory markers, higher levels of collagen repair compounds, increased blood flow, and activity of repair and remodeling cells in these tissues. Sexual Performance Another benefit of increasing nitric oxide levels is the improvement of blood flow to penile tissues for erectile function. Improved blood flow and small blood vessel dilation helps support normal sexual function. Grape Seed Extract Performa Plus also contains grape seed extract, a versatile and valued antioxidant. As a plant-based compound, grape seed extract provides a wide variety of benefits as an antioxidant, collagen strengthener, cardiovascular and metabolic support nutrient. Grape seed extract, like Nitrosigine®, also enhances beneficial nitric oxide balance, which supports vasodilation. Recent clinical trials demonstrated its benefit on blood pressure in healthy and obese men during rest and with moderate exercise. Another clinical trial showed grape seed extract enhanced blood vessel relaxation, provided endothelial lining and nitric oxide support, and supported heart health in normal body weight and obese adults. Grape seed extract has other benefits, too. This plant-based antioxidant supports healthy cholesterol metabolism, adipokines and insulin management, and regulates fat burning in white and brown adipose tissue. It also protects your gut lining barrier and promotes a healthy balance of intestinal flora. Animal studies show that grape seed extract helps modulate obesity clock genes found in white fat cells for healthy metabolism. It also helps reduce fatigue after exercise. Grape seed extract combined with Nitrosigine® makes Performa Plus great for all fitness levels desiring to improve metabolism, weight management, cardiovascular support, and tissue recovery, but there is more! Panax Ginseng Panax ginseng in Performa Plus provides another pillar of remarkable support. We provide a very high-grade of standardized Panax Ginseng C.A. Meyer extract which is also known as Korean or Asian ginseng. It provides a minimum 27% of ginsenosides, which are the most important active compounds of this prized tonic. Many products contain only 5% ginsenosides in their standardized extract. Panax ginseng has been used for over 4000 years in Asia to help assist the body in adapting to physical and emotional stress and fatigue. It is often used with other adaptogenic herbs like Eleutherococcus (American ginseng), holy basil, cordyceps, and rhodiola to help stress, fatigue, and cortisol management. A recent 2021 review study provided highly detailed effects of Panax ginseng on energy and fatigue management and why it is considered the “king of herbs.” Panax ginseng helps reduce fatigue by supporting antioxidant mechanisms, management of inflammatory compounds and metabolic waste, immune modulation, and boosts energy mechanisms. It aids with different types of fatigue and supports muscle comfort, sleep quality, appetite, and mood. Panax ginseng enhances the ability to exercise longer with less oxidative damage to mitochondria. Research showed that after four weeks of Panax ginseng use, participants experienced improvements in energy levels as well as increased glutathione levels and antioxidant activity. Panax Ginseng Additional Benefits Preliminary studies in menopausal women showed that Panax ginseng improved DHEA levels and naturally supported androgen/testosterone levels. This aids muscle strength, endurance, and stamina at a time when it is often more difficult to retain. Panax ginseng supports testosterone levels and male reproduction along with prostate and urinary flow concerns associated with aging. In addition, other research demonstrated that Panax ginseng counteracted negative hormone effects on testosterone, estrogen, and progesterone induced by BPA and other phalates during pregnancy. The unique combination of Nitrosigine®, grape seed extract, and Panax ginseng focuses on multi-dimensional performance. From the production boost of beneficial nitric oxide for muscles, blood vessels, mental focus, and recovery dynamics, to energy mechanisms and metabolic and hormonal support, these nutrients enhance your performance during exercise and act as stress buffering against the effects of age. Are you meeting your performance goals?


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